Presenilin cleaves the amyloid precursor protein (APP) at the _________proteolytic cleavage site.
a. Delta
b. Beta
c. Alpha
d. Gamma

Answers

Answer 1

Presenilin cleaves the amyloid precursor protein (APP) at the gamma proteolytic cleavage site. The correct answer is (D).

Amyloid-beta peptides are produced when presenilin cleaves APP at the gamma location. These peptides are crucial to the onset and development of Alzheimer's disease. The pathogenic amyloid-beta 42 peptide, which has a propensity to accumulate and form plaques in the brain, is released as a result of this cleavage, which takes place within the transmembrane region of APP.

A part of the -secretase complex, which is in charge of cleaving APP's transmembrane region, is presenilin. Multiple sites, including the site, are involved in this cleavage, which results in the release of A peptides with various lengths. The buildup of A peptides, especially the longer and more fibrillogenic forms like A 42, can result in amyloid plaques, a kind of amyloid.

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Related Questions

If the acceleration graph is a flat line, what does that tell you about the motion? Why?

Answers

It tells us that the motion is constant or stationary

How do humans influence the availability of renewable and non-renewable resources
on earth?
Please provide an example in your explanation.

Answers

Answer:

Humans use up many nonrenewable reacources every day, alongside renewable ones. One example of such is oil, oil takes millions of years to form, much longer than the amount of time it takes for us to use it up.

Explanation:

Hope this was helpful! :)

Which gas is most necessary for plants to do photosynthesis?

A. carbon dioxide

B. nitrogen

C. oxygen

Answers

QUESTION :::::

Which gas is most necessary for plants to do photosynthesis?

A. carbon dioxide

B. nitrogen

C. oxygen

ANSWER ::::

carbon dioxide

To perform photosynthesis, plants need three things: carbon dioxide, water, and sunlight. for photosynthesis. Carbon dioxide enters through tiny holes in a plant's leaves, flowers, branches, stems, and roots. Plants also require water to make their food.

Explanation:

CAN I GET THE CROWN PLEASE I HOPE IT HELPS THANKS

Saltatory conduction is aided by _____ located at _____.
glial cells; nodes of Ranvier
sodium and potassium channels; nodes of Ranvier
calcium channels; nodes of Ranvier
sodium-potassium pumps; terminal buttons

Answers

Saltatory conduction is aided by sodium and potassium channels located at the nodes of Ranvier.

Nodes of Ranvier are small gaps or spaces between the myelin sheaths along the axons of neurons. These nodes are rich in ion channels, including sodium and potassium channels. These ion channels play a crucial role in facilitating saltatory conduction.

When a nerve impulse reaches a node of Ranvier, the depolarization of the membrane opens voltage-gated sodium channels, allowing sodium ions to rush into the axon. This influx of sodium ions generates an action potential that rapidly propagates down the axon. As the action potential reaches the next node of Ranvier, the process repeats, allowing the impulse to "jump" from one node to the next.

The nodes of Ranvier are important because they are the only points along the myelinated axon where the ion channels are densely concentrated. This concentration of ion channels enables the efficient and rapid propagation of the nerve impulse through saltatory conduction.

It is worth noting that while glial cells (specifically, oligodendrocytes in the central nervous system and Schwann cells in the peripheral nervous system) are responsible for producing the myelin sheaths that aid saltatory conduction, they are not directly involved in the conduction process itself. Instead, they provide insulation and support to the axon, allowing for more efficient signal transmission.

Therefore, the correct answer is sodium and potassium channels, nodes of Ranvier.

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predict if a coelomate or an acoelmate would be larger

Answers

Answer:

Explanation:

A coelom is a hollow space surrounded by tissues. The basic structure of most animals comprises three tissue layers, an interior endoderm and an exterior ectoderm that are separated by a mesoderm. Typically, the endoderm forms the innermost digestive tract, the ectoderm the outermost skin layer, and the remaining internal organs are formed from the mesoderm. In derived animals, the endodermal tube is suspended from the dorsal and ventral surfaces by mesoderm, so as to leave open coeloms that allow circulation of fluids. Advanced circulatory systems develop from these coeloms.

The structural formulas of amino acids are the same EXCEPT for the A) amino group. B) side chain or R group. C) hydrogen bonding D) carboxyl group. E) alpha carbon

Answers

The structural formulas of amino acids are the same except for the side chain or R group, which differentiates one amino acid from another.

Answer choice B is correct. The structural formulas of amino acids consist of a central carbon atom, known as the alpha carbon, which is bonded to four different groups: an amino group (NH2), a carboxyl group (COOH), a hydrogen atom (H), and the side chain or R group.

The side chain varies among different amino acids, giving each amino acid its unique properties and chemical characteristics.

The amino and carboxyl groups are present in all amino acids, while the hydrogen atom and alpha carbon are also consistent components. Therefore, the side chain or R group is the distinguishing factor that sets one amino acid apart from another.

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Does the Earth have naturally occurring climate cycles, and if so, how
frequently?

Answers

Answer:

Earth has experienced cold periods (or “ice ages”) and warm periods (“interglacials”) on roughly 100,000-year cycles for at least the last 1 million years.

Explanation:

Tamesha plays tennis all day in the hot Sun and drinks very little. What effect will her behaviour have on the quantity and concentration of her urine? Explain your answer.

Answers

Tamesha's behavior will result in decreased quantity and increased concentration of her urine due to dehydration from inadequate fluid intake.

Tamesha's behavior of playing tennis all day in the hot sun and drinking very little will have significant effects on the quantity and concentration of her urine. Here's a step-by-step explanation:

Quantity of Urine: When Tamesha engages in intense physical activity and sweats heavily due to the hot sun, her body loses a significant amount of fluid. With limited fluid intake, there is less water available for the kidneys to produce urine. As a result, the quantity of her urine will decrease.Concentration of Urine: With reduced fluid intake and increased water loss through sweating, Tamesha is likely to become dehydrated. Dehydration triggers the release of antidiuretic hormone (ADH), which acts on the kidneys to reabsorb more water from the filtrate. This adaptive mechanism helps conserve water in the body, leading to a higher concentration of solutes in the urine. Consequently, the concentration of Tamesha's urine will increase.

Overall, Tamesha's behavior of playing tennis in the hot sun and drinking very little will result in a decrease in urine quantity and an increase in urine concentration due to dehydration and the body's efforts to conserve water.

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can a transformed organism pass on its new traits to its offspring

Answers

Yes, a transformed organism can pass on its new traits to its offspring. Transformation is the alteration of the genetic material of an organism by artificial means. It can occur naturally by the process of genetic recombination.

Recombination occurs when genetic material is exchanged between two different DNA molecules to produce new combinations of genes. Transformations can be passed on to the next generation of an organism. The new traits introduced in an organism by transformation can be transferred to its offspring. This is the reason why genetic engineering is considered an important tool in biotechnology to modify the genes of organisms. This can be done through a variety of techniques, such as gene insertion, gene deletion, or gene modification. In some cases, the new traits that are introduced into the organism can be passed on to its offspring.

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HELP WILL GIVE BRAINLIEST IF CORRECT: What effect do plants' roots
have on rock?
a. They hold it together
b. They weather it
c. They cause it to undergo chemical changes
d. They break it apart

Answers

Answer: C

Explanation: Reason why is because whenever the roots put pressure on the rock it cracks open and all the minerals release so it has to be going thru a chemical change because the roots receive the minerals from the rock or stone ...

Answer:

im guessing d but im not sure..,

Explanation:

When these roots grow, they exert pressure on the rock around them, causing the gaps to widen or even crack. Plant roots can also weather rock through chemical processes. When dead roots decompose, they release carbon dioxide; this is sometimes converted into carbonic acid, which chemically breaks down rock into soil.

Plants take in nitrogen by absorbing:
A. nitrogen molecules with sunlight during photosynthesis.
B. nitrogen gas from the air through their stomata.
C. nitrogen-containing macromolecules made by other organisms.
D. nitrogen-containing compounds made by bacteria from the soil.

Answers

Answer:

D

Explanation:

Plants take their nitrogen from the soil which would have been converted by bacteria ...not straight from the atmosphere

We apply Occam's Razor to scientific analysis of phylogenetic hypotheses because: O None of these answers are correct. o We know that convergence of traits rarely occurs. O The hypothesis with the fewest ad hoc assumptions is the most rejectable. O The simplest hypothesis often turns out to be correct.

Answers

That the simplest hypothesis often turns out to be true best describes why Occam's razor applies to the scientific analysis of phylogenetic hypotheses. Here option D is the correct answer.

Occam's Razor is a principle used in scientific analysis to choose between competing hypotheses or explanations. It suggests that all else being equal, the simplest hypothesis is usually the most likely to be correct.

The principle is attributed to the 14th-century philosopher William of Ockham, who stated, "Entities should not be multiplied without necessity." In the context of phylogenetic hypotheses, Occam's Razor is applied to guide the selection of the most plausible explanation for the evolutionary relationships among species.

A phylogenetic hypothesis is a proposed tree-like diagram that represents the evolutionary history and relatedness of organisms. Multiple competing hypotheses can be formulated based on different interpretations of available evidence.

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Complete question:

Which statement best describes why Occam's Razor is applied to scientific analysis of phylogenetic hypotheses?

A) None of these answers are correct.

B) We know that convergence of traits rarely occurs.

C) The hypothesis with the fewest ad hoc assumptions is the most rejectable.

D) The simplest hypothesis often turns out to be correct.

The periodic table divides elements according to similar properties-- example, metals and nonmetals a. Relationship questions: 1. Describe 4 properties that are common with metals and 4 properties common with nonmetals. 2. What happens to individual element properties of both metals and nonmetals when they bond together forming a mineral?

Answers

The periodic table divides elements according to similar properties-- example, metals and nonmetals.

The relationship between metals and nonmetals is explained below:1. Four properties that are common with metals and nonmetals:Metals1. Metallic elements have a shiny luster.2. Most metals are solid at room temperature.3. They have a high melting and boiling point.4. Metals have a high electrical conductivity.Non-Metals1. Most non-metals have no luster and are dull.2. Nonmetals can be in any state at room temperature: solid, liquid, or gas.3. Nonmetals have a low melting and boiling point.4. Nonmetals have low electrical conductivity.2. What happens to individual element properties of both metals and nonmetals when they bond together forming a mineral?

In a mineral, when individual element properties of both metals and nonmetals bond together, they result in a variety of new properties that depend on the type and proportion of elements involved in the mineral formation.

For example, the properties of both sodium (a metal) and chlorine (a nonmetal) alter when they bond together to form sodium chloride. Sodium chloride (NaCl) is white, tastes salty, is brittle, and is an excellent conductor of electricity. The individual properties of sodium and chlorine have merged into new properties in NaCl.

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What is the role of bitechnology in the environment

Answers

Answer:

i already answer but here you go again

it addresses environmental problems, such as the removal of pollution, renewable energy generation or biomass production, by exploiting biological processes.

Explanation:

A bacteria replicates every 30 minutes. How many bacteria are present after 4 hours?

Answers

Answer: 8 bacteria would be present after four hours.

Explanation:

Pls help due today, would be greatly appreciated.

Answers

For the first 2 rows it’s going to be the dominant phenotype. So “purple flowers” for the 1st and 2nd row and white flowers for the last one. For the first row on #17 it’s going to be “FF “and “ff” for the 2nd. Tongue roller is “TT” and non tongue roller is “tt.”

Which of the following factors will not influence an aquatic system's biological oxygen demand (BOD)?
Group of answer choices
a) The amount of inorganic nutrients in the system (e.g., nitrogen and phosphorous)
b) The time of year (i.e., the amount of sunlight available and the temperature)
c) Never mind – all of these will either directly or indirectly influence BOD
d) The availability of organic carbon sources
e) The blockage of wavelenths of light that are essential to photoautotrophs.

Answers

Factors that will not affect the influence of an aquatic system's biological oxygen demand are the blockage of wavelengths of light that are essential to photoautotrophs. Therefore, option " E". The amount of oxygen that is required for aerobic bacteria to decompose organic waste from water is measured as BOD.

The factors which influence the biological oxygen demand depend on the kind and amount of natural material present, the temperature, the pH, oxygen fixation, and furthermore the presence of microorganisms. These factors directly influence aquatic life.

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Which type of reproduction results in variation of offspring?

Answers

Answer:

sexual reproduction

Explanation:

sexual reproduction

In sexual reproduction, the genetic material of two individuals is combined to produce genetically diverse offspring that differ from their parents. Fertilization and meiosis alternate in sexual life cycles.

How do toothed whales produce echolocating sounds?

Answers

Answer:

As the lips vibrate, the sound is transmitted via the whale's 'melon' – fatty tissue that makes up its forehead. This tissue has the same acoustic properties as water. ... Toothed whales can direct sound by bouncing it off air sacs in their nose and possibly by using face muscles to alter the shape of the melon.

Explanation:

After using a chemical mutagen to generate mutations in a dna sequence, scientists noted a mutation from c to t at the 10th position within the coding region of a gene. this mutation led to a change of proline into serine at the fourth position in the resulting peptide. using this information and the sequences listed below, select all the types of mutations that occurred.

Answers

Answer:

substitution, missense mutation, and transition

Explanation:

A mutation is any change in the genetic information of an organism. A substitution is a point mutation by which a single nucleotide base pair is replaced by a different nucleotide. Moreover, a missense mutation is a point mutation that results in the incorporation of a different amino acid in the polypeptide chain since this mutation generates a new codon which codes for a different amino acid. Finally, a transition is a point mutation where a purine (either Adenine or Guanine) is changed to another purine, or a pyrimidine (either Thymine or Cytosine) is changed to another pyrimidine (in this case, Cytosine is changed to Thymine).

what would a student researcher expect to see around the bacterial patches that kill the safe relatives?

Answers

A student researcher might look at the various symptoms in the surroundings while examining bacterial patches that kill safe relatives.

Denial zones, which are areas devoid of development or colonies of protected relatives, will be the most prominent feature. This region will display the effects of bacteria, whether by direct bacterial killing or growth suppression. The bacterial patches themselves, however, will show clear growth and colonization.

There would be a progressive decline in bacterial concentration as researchers moved away from the patch, which would lead to a decrease in colony density. The regular growth patterns of other creatures or microbes would be unaffected by the patch. Additionally, the absence or low presence of protected relatives around bacterial patches can have ecological effects, which can alter community dynamics.

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Definition of fruits

Answers

Answer:

Fruit, the fleshy or dry ripened ovary of a flowering plant, enclosing the seed or seeds

Explanation:

Hope this helps

What is the relationship between gene regulation and mutation?

Answers

Answer:

They include: mutations in transcription factors and signalling proteins; mutations in factors that regulate the methylation of DNA and associated histone proteins; mutations in the protein complex cohesin, which regulates chromatin structure; and mutations in proteins involved in splicing

Explanation:

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?????????? helppppppppp

Answers

Answer:

Nuclear Energy from uranium is non-renewable

Hydrogen from water is renewable

Wind energy from air is renewable

Solar energy from the Sun is renewable

Fossil fuel from coal is non-renewable

Explanation:

Energy resources refers to those materials or items from which energy can be derived. Energy resources are generally classified into renewable and non renewable energy resources.

Renewable energy resources are those types of resources which can be renewed or replenished as they are being used up. Renewable energy is often referred to as clean energy and comes from natural sources or processes. Examples of these renewable energy resources are energy from wind, water and sunlight.

Non-renewable energy resources are those types of resources which are not easily renewed or replenished as they are being used up. Examples include energy from fossil fuels such as petroleum and natural gas, coal, nuclear energy from radioactive materials, etc.

From the given table:

Nuclear Energy from uranium is non-renewable

Hydrogen from water is renewable

Wind energy from air is renewable

Solar energy from the Sun is renewable

Fossil fuel from coal is non-renewable

The generative nucleus divides by mitosis in the pollen tube. State the importance of the process.​

Answers

Explanation:

The binucleate pollen grain results from the microspore mitosis leading to formation of a generative cell and a vegetative (or « pollen tube ») cell, both included within the pollen cell wall; the generative nucleus divides to form the two sperm nuclei in the pollen tube.

identifying an autosomal recessive mutation in a mutagenic screen in drosophila requires identification of a mutant in the f3 generation. if testing for a sex-linked recessive lethal mutation (e.g., cn) using a balancer chromosome such as cncyo, in which generation can lines with mutations be identified?

Answers

To identify a sex-linked recessive lethal mutation using a balancer chromosome such as cncyo in Drosophila, lines with mutations can be identified in the F1 generation.

A balancer chromosome is a specialized chromosome used in Drosophila genetics to maintain the integrity of a specific genotype during breeding.

In the case of a sex-linked recessive lethal mutation, the balancer chromosome contains multiple inversions that prevent recombination and help maintain the recessive lethal mutation along with visible markers.

The cncyo balancer chromosome, for example, carries the cn mutation, which is recessive and lethal when homozygous.

When performing crosses with a balancer chromosome, the F1 generation will inherit one copy of the balancer chromosome along with the recessive lethal mutation.

The visible markers on the balancer chromosome, such as eye color or wing shape, can be used to identify the presence of the balancer chromosome and, by extension, the presence of the recessive lethal mutation.

If a line exhibits the phenotypic markers associated with the balancer chromosome, it indicates the presence of the recessive lethal mutation.

Therefore, lines with mutations can be identified in the F1 generation when testing for a sex-linked recessive lethal mutation using a balancer chromosome in Drosophila.

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Place the steps of bacterial transformation in order of occurrence. Not all items will be placed. Bacteria encounters foreign DNA from the environment. Foreign DNA is duplicated with bacterial DNA after the next round of cell division. Answer Bank DNA binds to the DNA-binding complex Enzymes separate double-stranded DNA into single strands A single-stranded fragment of DNA is imported into the cell. The DNA fragment recombines into a homologous region of the bacterial chromosome A phage injects DNA into the bacteria.

Answers

Bacteria encounter foreign DNA from the environment. A phage injects DNA into the bacteria. Enzymes separate double-stranded DNA into single strands. DNA binds to the DNA-binding complex. A single-stranded fragment of DNA is imported into the cell.

To properly order the steps of bacterial transformation, I will arrange them based on the chronological sequence of events: Bacteria encounters foreign DNA from the environment: In the process of bacterial transformation, bacteria come into contact with foreign DNA that is present in their surroundings.

A phage injects DNA into the bacteria: Sometimes, bacteriophages (viruses that infect bacteria) can inject their own DNA into bacterial cells. Enzymes separate double-stranded DNA into single strands: Once foreign DNA enters the bacterial cell, enzymes called endonucleases act upon the double-stranded DNA, separating it into single strands.

DNA binds to the DNA-binding complex: The single-stranded fragments of foreign DNA bind to a DNA-binding complex within the bacterial cell. This complex helps protect the incoming DNA and assists in its integration. A single-stranded fragment of DNA is imported into the cell: The bound single-stranded fragment of foreign DNA is imported into the bacterial cell's cytoplasm, allowing it to interact with the bacterial chromosome.

The DNA fragment recombines into a homologous region of the bacterial chromosome: Recombination occurs between the imported foreign DNA fragment and a complementary region of the bacterial chromosome. This integration results in the insertion of the foreign DNA into the bacterial genome.

Foreign DNA is duplicated with bacterial DNA after the next round of cell division: As the bacterium undergoes cell division, the integrated foreign DNA is replicated along with the bacterial chromosome, allowing the transformed genetic material to be inherited by daughter cells.

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Over 400 years ago, the bark of the cinchona tree was discovered to contain a chemical compound called quinine. Quinine was, and still is, used to cure and prevent malaria. This is an early example of ____________________.

a. biotechnology

b. scientific modeling

c. genetic engineering

d. genomics

Answers

Answer:

A.

Explanation:

What are the benefits of biodiversity? A. A variety of resources B. Healthier ecosystems C. Both A & B

Answers

Answer:

C. both A and B

Explanation:

Both a and b
They provide positive benefits for the environment

b) What is one reason that a virus that spends a long time in the lysogenic cycle could be more
dangerous to humans than a virus that does not? (3 points)
I

Answers

Answer:

because it takes longer to process so it would stay longer so it's more dangerous

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A 26-year-old female patient was involved in an automobile accident and the air bag deployed, fracturing her nasal septum. She feels fortunate to have escaped serious injury, but is concerned when she is informed that only local anesthetic will be used during the procedure. In preoperative holding, she reports her fears of feeling pain during the case to the CST.What surgical procedure will be performed to repair the patient's fractured septum?What steps will be taken to ensure that the surgical site is properly anesthetized?What medications and supplies will the CST expect the surgeon to use to administer anesthesia?What reassurances can the OR team give the patient to alleviate her fears? Use the future tense to describe what you think your soulmate (alma gemela) will be like. This person could be your romantic soulmate or a lifelong best friend. What physical and personality characteristics will they have? Where do you think youll meet them? What interests will you share? Your response must contain 5 complete and detailed sentences in Spanish. Use 5 different verbs in your response.Your response needs to be at least 30 seconds in length. Consider a trader who takes a long position in a six-month futures contract on the euro. The forward rate is $1.75 = 1.00; the contract size is 62,500. At the maturity of the contract the spot exchange rate is $1.65 = 1.00.a. The trader has lost $625.b. The trader has lost $6,250.c. The trader has made $6,250.d. The trader has lost $66,287.88 Portable Power Inc. buys portable generators for $470 and sells them for $750. They pay a sales commission of 5% of sales revenue to their sales staff. Portable Power Inc. pays $6,000 a month rent for The actual error when the first derivative of f(x) = x - 21n x at x = 2 is approximated by the following formula with h = 0.5: - 3f(x) - 4f(x - h) + f(x - 2h) f'(x) = 12h Is: 0.00475 0.00142 0.00237 0.01414 Bunnell Corporation is a manufacturer that uses job-order costing. On January 1, the companys inventory balances were as follows:Raw materials $ 72,500Work in process $ 18,200Finished goods $ 46,500The company applies overhead cost to jobs on the basis of direct labor-hours. For the current year, the companys predetermined overhead rate of $15.50 per direct labor-hour was based on a cost formula that estimated $620,000 of total manufacturing overhead for an estimated activity level of 40,000 direct labor-hours. The following transactions were recorded for the year:Raw materials were purchased on account, $628,000.Raw materials used in production, $598,000. All of of the raw materials were used as direct materials.The following costs were accrued for employee services: direct labor, $570,000; indirect labor, $150,000; selling and administrative salaries, $266,000.Incurred various selling and administrative expenses (e.g., advertising, sales travel costs, and finished goods warehousing), $418,000.Incurred various manufacturing overhead costs (e.g., depreciation, insurance, and utilities), $470,000.Manufacturing overhead cost was applied to production. The company actually worked 41,000 direct labor-hours on all jobs during the year.Jobs costing $1,717,900 to manufacture according to their job cost sheets were completed during the year.Jobs were sold on account to customers during the year for a total of $3,225,000. The jobs cost $1,727,900 to manufacture according to their job cost sheets.Required:1. What is the journal entry to record raw materials used in production? (If no entry is required for a transaction/event, select "No journal entry required" in the first account field.)2. What is the ending balance in Raw Materials?3. What is the journal entry to record the labor costs incurred during the year? (If no entry is required for a transaction/event, select "No journal entry required" in the first account field.)4. What is the total amount of manufacturing overhead applied to production during the year?5. What is the total manufacturing cost added to Work in Process during the year?6. What is the journal entry to record the transfer of completed jobs that is referred to in item g above? (If no entry is required for a transaction/event, select "No journal entry required" in the first account field.)7. What is the ending balance in Work in Process?8. What is the total amount of actual manufacturing overhead cost incurred during the year?9. Is manufacturing overhead underapplied or overapplied for the year? By how much?10. What is the cost of goods available for sale during the year?11. What is the journal entry to record the cost of goods sold referred to in item h above? (If no entry is required for a transaction/event, select "No journal entry required" in the first account field.)12. What is the ending balance in Finished Goods?13. Assuming that the company closes its underapplied or overapplied overhead to Cost of Goods Sold, what is the adjusted cost of goods sold for the year?14. What is the gross margin for the year?15. What is the net operating income for the year? Which of the following uses packet switching? A) Dial-up telephone circuits. B) Leased line circuits. C) Both A and B D) Neither A nor B and more Which of the following examples would be the least effective closing for 2p the refusal of a request? O A) Your project does sound fascinating. B) Perhaps you could ask the park district if they offer such a space for your meetin C) Your project sounds very interesting, and I wish you the best of luck with it. OD) D) Again, I regret that we must refuse. E) I recommend applying for our arts grant instead, which might better fit your request The Naples Newspaper completes production of its daily edition by 5 a.m. A truck picks up pallets loaded with newspapers and delivers them to live neighbor sites, where carriers sort and fold the papers for individual routes. The mileage between locations is shown in the table below. Currently, the truck picks up the number of pallets required by each customer at the factory, delivers them, and then returns to the factory to get the papers for the next customer (i.e., current route 0-1-0-2-0-3-0-4-0). The truck always returns to Scottsville and gets 10 miles per gallon using diesel fuel. A truck can carry up to 16 pallets. A gallon of diesel fuel is $3.00. The newspaper operates 365 days per year. Case 11: Levi's Move to Sustainability Levi Strauss is launching an effort to slash the environmental impact of the factories world-wide that make its apparel, reports The Wall Street Journal(Aug. 1, Broadcom Inc is expected to have EPS of $2 and ROE of 0.1777 in the coming year. If the firm is expected to continue to retain 80% of earnings for the foreseeable future, what's the intrinsic value of the stock if the required return is 11%? The Reynolds Corporation buys from its suppliers on terms of 2/19, net 60. Reynolds has not been utilizing the discounts offered and has been taking 60 days to pay its bills. Ms. Duke, Reynolds Corporation's vice president, has suggested that the company begin to take the discounts offered. Duke proposes that the company borrow from its bank at a stated rate of 24 percent. The bank requires a 11 percent compensating balance on these loans. Current account balances would not be available to meet any of this compensating balance requirement. a. Calculate the cost of not taking a cash discount. (Use a 360-day year. Do not round intermediate calculations. Input your answer as a percent rounded to 2 decimal places.) Cost of not taking a cash discount % b. What is the effective rate of interest on the bank loan? (Use a 360-day year. Do not round intermediate calculations. Input your answer as a percent rounded to 2 decimal places.) Accordi ing to the mean-variance criterion, which one of the following investments dominates the others? A. E(r) = 0.15; Variance = 0.20 B. E(r) 0.10; Variance- 0.20 C. E(r) = 0.25; Variance 0.20 D. E(r) 0.10; Variance 0.25 E. E(r)-0.15; Variance = 0.25 20. According to the Markowitz portfolio theory, the optimal risky portfolio refers to: A. The efficient portfolio that has the minimum variance B. The efficient portfolio that has the highest Sharpe ratio C. The efficient portfolio that has the highest expected return D. All portfolios that lie on the efficient frontier The movie poster for what best picture winner features a man sitting alone on a park bench? 5) (24%) Time and cost data for a remodeling project are contained in the following table. Indirect project costs are $90 per day. Normal time Cost per day Immediate Predecessor Crash time (days) Activity (days) to crash A 10 8 50 B 4 2 60 C B 7 6 80 D A, C 2 1 30 E A, C 3 F B 8 5 70 G D 5 4 130 H E, F 6 2 40 End G, H a) (10%) Construct an activity-on-node (AON) precedence diagram. What is the project duration if only normal activity times are used? b) (14%) Determine an optimum crashing plan. Show your crashing sequence and the resulting total crashing cost. Suppose the price of tennis balls rises by 8%. As a result, the quantity of tennis balls demanded decreases by 12%. What is the absolute value of the price elasticity of demand for tennis balls? Does the Glo-Germ activity provide a good model of how a disease such as seasonal flu (influenza) spreads in a community? Explain why and/or why not A 25.0 mL sample of an unknown HBr solution is titrated with 0.100 M NaOH. The equivalence point is reached upon the addition of 18.88 mL of the base. What is the concentration of the HBr solution? a. 0.0755 M b. 0.0376 M c. 0.100M d. 0.0188 M Suppose you are evaluating a project with the expected future cash inflows shown in the following table. Your boss has asked you to calculate the project's net present value (NPV). You don't know the project's initial cost, but you do know the project's regular, or conventional, payback period is 2.50 years. If the project's ~WACC~ is 10%, the project's NPV (rounded to the nearest dollar) is: $408,976 $391,194 $355,631 $373,413 Which of the following statements indicate a disadvantage of using the regular payback period (not the discounted payback period) for capital budgeting decisions? Check all that apply. The payback period is calculated using net income instead of cash flows. The payback period does not take the project's entire life into account. The payback period does not take the time value of money into account. 1. For all named stors that have made landfall in the United States since 2000, of interest is to determine the mean sustained wind speed of the storms at the time they made landfall in this scenario, what is the population of interest?2. Based on the information in question 1, what is the parameter of interest? A. The average sustained wind speed of the storms at the time they made landfall B. The mean of sustained wind speed of the storms C. The proportion of the wind speed of storm D. The mean usustained wind speed of the storms at the time they made landfall E. The proportion of number of storms with high wind speed3. Consider the information presented in question 1. What type of characteristic is mean sustained wind speed of the storms at the time they made landfall? A. Categorical variable B. Constant C. Discrete quantitative variable D. Continuous quantitative variable