identify the incorrect statement describing the sample sizes and time frames for conducting the various stages of human clinical trials: group of answer choices stage 3: 500-50,000 individuals - usually 4-5 years stage 4: millions of individuals - between 1-2 years stage 1: 5-50 individuals (healthy, young); few weeks to months stage 2: 50-500 individuals (cross section, more cohorts) - months to years

Answers

Answer 1

The incorrect statement is  50-500 individuals (cross section, more cohorts) - months to years

The answer provided above has been developed in a clear step by step manner.

Stage 1: 5-50 individuals (healthy, young); few weeks to months is correct considering the hypothesis

Second option is incorrect

Stage 2: 50-500 individuals (cross section, more cohorts) - months to years

Stage 3: 500-50,000 individuals - usually 4-5 years is also correct

Stage 4: millions of individuals - between 1-2 years is also correct

Appropriate sample size generally depends on the specified statistical hypotheses and a few study design parameters. These include the minimal meaningful detectable difference (effect size), estimated measurement variability, desired statistical power, and significance level

Therefore,50-500 individuals (cross section, more cohorts) - months to years can't be used to describe the sample sizes and time frames for conducting the various stages of human clinical trials

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Related Questions

Evaluate. Write your answer as a whole number or as a simplified fraction.

Answers

Answer:

121

Step-by-step explanation:

11^6/11^4

= 11^(6-4)

= 11^2

= 121

f(x)=x^2+x and g(x)=1/x+1 find the rules for (f o g)(x) and (g o f)(x) and give the domain of each composite function

Answers

The composite functions of  (f o g)(x), (g o f)(x) and their domains in the function f( x ) = x² + x and  g( x ) = 1/(x+1) are (x+2) / (x+1)², Domain: {x|x ≠ -1 } and 1/(x² + x + 1 ), Domain: {x|x ∈ R } respectively.

What are the composite result function and domain of (f o g)(x) and (g o f)(x) in the given function?

A function is simply a relationship that maps one input to one output.

Given the data in the question;

f( x ) = x² + xg( x ) = 1/(x+1)(f o g)(x) = ?(g o f)(x) = ?

First, set up the composite result function (f o g)(x).

(f o g)(x) = f( g(x) )

f( x ) = x² + x

f( g(x) ) = f( 1/(x+1) )  = ( 1/(x+1) )² + 1/(x+1)

Apply product rule to simply

f( g(x) ) = 1² /(x+1)² + 1/(x+1)

f( g(x) ) = (1 + x + 1 )/ (x+1)²

f( g(x) ) = (x+2) / (x+1)²

Next, find the domain by equating the denominator to 0 and solve for x.

x + 1 = 0

x = -1

Domain: {x|x ≠ -1 }

For (g o f)(x), set up the composite result function (g o f)(x).

(g o f)(x) = g( f(x) )

g( x ) = 1/(x+1)

g( f(x) ) = g( x² + x ) = 1/( (x² + x) + 1 )

g( f(x) ) = 1/( (x² + x) + 1 )

g( f(x) ) = 1/(x² + x + 1 )

Next, find the domain by equating the denominator to 0 and solve for x.

x² + x + 1 = 0

x = ( -1±√(1² - 4 ×(1×1) ) / (2 × 1 )

x = (-1±i√3)/2

x = (-1+i√3)/2, (-1-i√3)/2

Hence,

Domain is set of all real numbers.

Domain: {x|x ∈ R }

Therefore the composite functions and their domain are (x+2) / (x+1)², Domain: {x|x ≠ -1 } and 1/(x² + x + 1 ), Domain: {x|x ∈ R }.

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Pot the points (4, 4), (8, 4), (3, 1), and (7, 1) on the coordinate plane.Use the points to draw two parallel, horizontal segments. Label theendpoints of one segment A and B. Label the endpoints of the othersegment C and D What is the distance between points A and B?What is the distance between points C and D

Answers

Solution

The diagram below shows what is needed

As shown above

distance between points A and B is

[tex]4[/tex]

distance between points C and D is

[tex]4[/tex]

Which expressions are equivalent to ✓-27?
3i√3
91√√/3
O √27i
O i√27
3√/91²

Answers

The expression for [tex]\sqrt{-27}[/tex] is 3i[tex]\sqrt{3}[/tex]

What is an expression?

Expression or mathematical expression is a finite combination of symbols that is well-formed according to rules that depend on the context.

given [tex]\sqrt{-27}[/tex] we know that

3 multiplied by 9 gives 27 and the square root of 9 is 3

we can write

[tex]\sqrt{-3(3)(3)}[/tex]

or [tex]3\sqrt{-3}[/tex]

square root of minus gives iota

we get,

[tex]3i\sqrt{3}[/tex]

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y=x+2 find the coordinates of the x and y intercept

Answers

All the points are P1=(0, 2), P2= (1,3), P3(2,4), P4(3,5 ), and P5(4,6).

y=x+2 is obtained function through the equation y-x=2.

Consider the value of X=0 for P1.

Y= 0+2

Y=2

If X=0, then Y=2.

∴ (0, 2)

Consider the value of X=1 for P2.

Y=1+2

Y=3

If X=1, then Y=3

∴ (1,3)

Consider the value of X=2for P3.

Y=2+2

Y=4

If X=2, then Y=4

∴ (2,4)

Consider the value of X=3for P4.

Y=3+2

Y=5

If X=3, then Y=5.

∴ (3,5 )

Consider the value of X=4 for P5.

Y=4+2

Y=6

If X=4, then Y=6.

∴ (4,6)

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Find the points on the graph of[tex]x^{2/3}[/tex] + [tex]y^{2/3}[/tex] = 1 where the tangent line has slope 1

Answers

Any point satisfying the relation y = -[1 - (∛x²)]²(1/(∛x)) will be points on the graph where the tangent line has slope 1.

What is the slope of a given line?
A line's slope in mathematics is defined as the ratio of the change in the y coordinate to the change in the x coordinate. Both the net change in the y-coordinate and the net change in the x-coordinate are denoted by y and x, respectively.
Consequently, the formula for the change in y-coordinate with respect to the change in x-coordinate is the slope of a line is represented by the expression m = change in y/change in x =Δy/Δx.
Additionally, the slope of the line can be shown as tan θ = Δy/Δx
So, the slope of a line is tan θ.

The given equation is: (∛x²) + (∛y²) = 1
Therefore, (∛y²) = 1 - (∛x²) ⇒ y² = [1 - (∛x²)]³
Differentiating the equation formed with respect to x, we get
2y(dy/dx) = 3[1 - (∛x²)]²(-2/3)(1/(∛x)) ⇒ dy/dx = (-1/y)[1 - (∛x²)]²(1/(∛x)) -(i)
Given, the slope of the tangent line is = 1 -(ii)
Thus, equating (i) and (ii), we get,
(-1/y)[1 - (∛x²)]²(1/(∛x)) = 1 ⇒ y = -[1 - (∛x²)]²(1/(∛x))
Therefore any point satisfying the relation y = -[1 - (∛x²)]²(1/(∛x)) will be points on the graph where the tangent line has slope 1.

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i need the right answers please help

Answers

Answer:

To what please

Step-by-step explanation:

I am here to help you so please send your questions

Let f be the function given by f(x) = x + [tex]\frac{\sqrt{x+1} }{x-1}[/tex]
Find and simplify f(3).
Responses
A f(3) = 5
B f(3) = 3 + 2[tex]\sqrt{2}[/tex]
C f(3) = 3 + [tex]\sqrt{2}[/tex]
D f(3) = 4

Answers

By evaluating f(x) in x = 3, we will get that:

f(3) = 4

Thus the correct option is D:

How to evaluate the function in x = 3?

Here we have the following function:

[tex]f(x) = x + \frac{\sqrt{x + 1} }{x - 1}[/tex]

We want to get f(3), and to get that, we just need to replace all the "x" in the equation by the number 3, we will get:

f(3) = 3 + (3 + 1)/(3 - 1)

f(3) = 3 + √4/2 = 4

With this, we can conclude that the correct option is D:

f(3) = 4.

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45. Maury bought concert tickets at the Ticket Outlet. He paid $12 for each
ticket, plus a $5 service charge for the whole set of tickets. The total cost
was $77. How many tickets did he buy? 3-11

Answers

Using mathematical operations, Maury bought 6 tickets at the Ticket Outlet if he paid $77 at $12 each.

What are the mathematical operations?

The basic mathematical operations are addition, subtraction, multiplication, and division.

These basic operations are used to manipulate numbers and variables in mathematical expressions to produce mathematical results.

The first mathematical operation used here is the subtraction operation.  

After subtracting the fixed cost from the total cost, the difference is the total variable cost.

This difference is then divided by the unit variable cost to get the number of tickets.

The unit cost of the ticket = $12

The service charge (fixed cost) = $5

The total cost = $77

The number of tickets bought = 6 ($77 - $5)/$12

Thus, using mathematical operations, Maury did buy 6 tickets for $77.

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Bricklayers use the formula n = 7th to estimate the number n
of bricks needed to build a wall of length and height h, where and hare in
feet. Solve the formula for h. Estimate the height of a wall 28 ft long that requires
1568 bricks.

(Round to the nearest tenth if necessary)

Answers

Answer: the answer is ..

Step-by-step explanation: fec r/sm mkdnjervc


(2t + 5x 3) + (-9t - 4x + 7)

Answers

[tex]=2t+5x+3-9t-4x+7\\=2t-9t+5x-4x+3+7\\=-7t+x+10[/tex]

Be aware I used the plus sign for 3 since you DID NOT insert the sign. For Future purposes Be careful.

Answer: -7t+x+10 (if the 3 in your equation is positive)

Step-by-step explanation: Add all like variables and integers.

Answer the question in the photo for EASY points ( 20 points )

Answers

Answer: 7921   123569 5410

Step-by-step explanation:

1. 7912

2. 123569

3. 5210

Find sin 8, cot0, and csc0, where 8 is the angle shown in the figure.
Give exact values, not decimal approximations.
Continue
25
0
sin 0
11

cot 8 = 0
CSC8 = 0

Answers

Answer:

sinTheta = 24/25

cotTheta = 7/24

cscTheta = 25/24

Step-by-step explanation:

Use pythagorean thm or pythagorean triples to find the missing side of the triangle.

7^2 + x^2 = 25^2

49 + x^2 = 625

x^2 = 576

x = 24

The third side of the triangle is 24. We'll need this in a sec.

The marked angle is called theta. That 0 with a belt is greek letter theta. They could just call it angleA or angleB or whatever. Its name is just theta no big deal.

25 is the hypotenuse (longest side). The side that's 7 units long is one of the pieces that makes up AngleTheta. So the 7 is "adjacent" to theta. The other leg, 24, is "opposite" from theta.

sinTheta is a ratio. It is OPPOSITE/HYPOTENUSE

sinTheta = 24/25

cotTheta is tanTheta flipped over.

tanTheta is OPP/ADJACENT

so...

cotTheta =

ADJ/OPP

=7/24

Last, cscTheta is sinTheta flipped over.

We already found sinTheta, so flip it over.

cscTheta = 25/24

SOH-CAH-TOA is supposed to help you memorize the ratios for sine (opp/hyp), cos (adj/hyp), and tan (opp/adj).

The math word for "flipped over" is reciprocal.

csc is the reciprocal of sin

sec is the reciprocal of cos.

cot is the reciprocal of tan.

Good luck! Hope this helps!

If f(x) = –2x+4 Evaluate the function when x= -3. f(-3) = ?

Answers

Answer:

f(-3)=10

Explanation:

Given the function:

[tex]f\mleft(x\mright)=-2x+4[/tex]

When x = -3

[tex]\begin{gathered} f(-3)=-2(-3)+4 \\ =6+4 \\ =10 \end{gathered}[/tex]

It took Elsa 18 minutes to make 3 bookmarks.

Which of the following pairs of equivalent fractions could be used to determine how many bookmarks she can make in 90 minutes?


Answers

Hope this answer helps:

Elsa took time to make 3 bookmarks=18 minutes

Time Elsa took for one minute= 18/3
=6

Total bookmarks mad by Elsa in 90 minutes=90/6
=15 bookmarks
The pair of equivalent fractions would be option A.) “3/18 = b/90.”

The fraction 3/18 shows 3 bookmarks were made in 18 minutes. With this proportion, we can set up an equivalent fraction to find the number of bookmarks made in 90 minutes:

3/18 = b/90,

where 90 represents the time it took in minutes and b represents how many bookmarks were made.

We can divide 18 and 3 by 3 separately to identify the unit rate:

18 / 3 = 6

3 / 3 = 1

When solving, we get 1/6 as our unit rate. Because the relationship is proportional, we know that 1/6 must equal b/90.

1/6 = b/90

1 • 90 = 90

6 • ? = 90

90 / 6 = 15

b = 15

Answer Recap: Option A is correct. If needed, b = 15.

Which sequence exhibits the similarity between rectangles ABCD which A’B’C’D’ shown in the coordinates plane below

Answers

The sequence of transformation that exhibits the similarity between the rectangles ABCD and rectangle A'B'C'D' is the option C.

C. Rectangle ABCD is reflected across the y-axis and then dilated by a scale factor of 2 with the center of dilation at the origin to obtain rectangle A'B'C'D'

What is a reflection transformation in geometry?

A reflection transformation of an object gives or produces the mirror image of the object about a specified line.

The coordinates of the points of the rectangle ABCD obtained from the graph are; A(-4, -4), B(-4, 4), C(2, 4), and D(2, -4).

The coordinates of the image of the rectangle ABCD (rectangle (A'B'C'D') are; A'(8, -8), B'(8, 8), C'(-4, 8) and D'(-4, -8)

The coordinates of the reflection of the point (x, y), following a reflection across the y-axis is the point (-x, y)

The vertices of the image of rectangle ABCD formed following a reflection across the x-axis are therefore;

A(-4, -4)  [tex]\underrightarrow{R_{x-axis}}[/tex] A''(4, -4)

B(-4, 4)  [tex]\underrightarrow{R_{x-axis}}[/tex] B''(4, 4)

C(2, 4)  [tex]\underrightarrow{R_{x-axis}}[/tex] C''(-2, 4)

D(2, -4) [tex]\underrightarrow{R_{x-axis}}[/tex] D''(-2, -4)

The coordinates of the point (x, y) following a dilation by a scale factor of k, with the center of dilation at the origin is (k·x, k·y)

The dilation of the image of the rectangle ABCD by a scale factor of 2 gives;

A''(4, -4)  [tex]\underrightarrow{D_{2}}[/tex] (2×4, 2×(-4)) = A'(8, -8)

B''(4, 4)  [tex]\underrightarrow{D_{2}}[/tex] (2×4, 2×(4)) = B'(8, 8)

C''(-2, 4)  [tex]\underrightarrow{D_{2}}[/tex] (2×(-2), 2×(4)) = C'(-4, 8)

D''(-2, -4)  [tex]\underrightarrow{D_{2}}[/tex] (2×(-2), 2×(-4)) = D'(-4, -8)

The points of the image of rectangle ABCD following a a reflection and a dilation are A'(8, -8), B'(8, 8), C'(-4, 8) and D'(-4, -8), which are the same as the coordinates of the points of the given rectangle A'B'C'D'

The correct option is therefore option C;

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y = 2 |x|
Graph the following linear inequalities

Answers

Mathematical expressions known as linear inequalities compare two expressions using the inequality symbol. The expression may be either a numerical or an algebraic expression, or it may be both.

What is meant by linear inequalities?

Addition, subtraction, multiplication, and division are the four types of operations that can be performed on linear inequalities. Equivalent inequality refers to linear inequalities with the same solution. Both equality and inequality are subject to laws. For inequality involving smaller than or equal to () and greater than or equal to (), all the principles listed below apply. Let's look at some of the key inequality rules for all these operations before learning how to solve linear inequalities.

As with multi-step linear equations, start by separating the variable from the constants when resolving multi-step linear inequalities with one variable. According to the laws of inequality, it is crucial that we remember to flip the inequality sign when multiplying or dividing with negative values while resolving multi-step linear inequalities.

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Create three probability application problems of your own. Solve your problems. Explain your answers.

Answers

The required problems on probability application are detailed below.

Probability is the study of chance represented as a proper fraction between 0 and 1 .  

The manufacturing process of a particular rugby ball consists of two parts, a leather covering and a rubber bladder. The probabilities of defect in the leather covering is 5% and the probability of the rubber bladder is 15% respectively. What is the probability that the assembled Rugby ball will not have any defect.

Let A and B denote the event that  a rugby ball is defective due to defects in the leather covering and the rubber bladder respectively.

Then we can say that  P(A) = 5 / 100 = 1 / 20  and

P(B) = 15 / 100 = 3 / 20

Therefore  P(A') = 1 - 1/20 = 19/20 and P(B') = 1 - 3 / 20 = 17 / 20.

P(A') and  P(B') gives us the probabilities that the rugby ball will not have defective parts respectively.

Therefore the probability that the assembled product will not have any defect is:

P(A') ×  P(B')

[tex]=\frac{19}{20} \times \frac{17}{20}\\\\=\frac{323}{400} \\\\=0.8075[/tex]

Therefore the probability that the rugby ball will not have any defect is 80.75% .

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Which point is a solution to the system of linear equations?

y = −x + 3
2x − y = 6

(3, 0)
(3, −1)
(0, 3)
(−1, 3)

Answers

The ordered pair which is a solution to the system of linear equations is: A. (3, 0).

How to determine the solution?

In order to determine a solution to the system of linear equations, we would have to test the given ordered pairs by substituting their values into the linear equations as follows;

For ordered pair (3, 0), we have:

y = −x + 3

0 = -3 + 3

0 = 0 (True).

2x − y = 6

2(3) - 0 = 6

6 - 0 = 6

6 = 6 (True).

For ordered pair (3, -1), we have:

y = −x + 3

-1 = -3 + 3

-1 = 0 (False).

For ordered pair (0, 3), we have:

y = −x + 3

3 = 0 + 3

3 = 3 (True).

2x − y = 6

2(0) - 3 = 6

0 - 3 = 6

-3 = 6 (False).

For ordered pair (-1, 3), we have:

y = −x + 3

3 = -1 + 3

3 = 2 (False).

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Translate this sentence into an equation.
The difference of Janelle's height and 9 is 65
Use the variable j to represent Janelle's height.

Answers

Step-by-step explanation:

Translate this sentence into an equation. The difference of Janelle's height and 9 is 65. Use the variable j to represent Janelle's height.

j - 9 = 65

to solve:

j - 9 = 65

add 9 to both sides:

j - 9 + 9 = 65 + 9

j = 74

63= 4w + 15 solve for w and simplify your anwser as much as possible.

Answers

Answer:

w is 59

Step-by-step explanation:

63-4 =59 and this should be the answer your looking for

Answer:

w=12

Step-by-step explanation:

63+4w+15

collect like terms

63-15=4w

48=4w (divide all through by 4)

w=12

HELP PLEASE!!A(5,1), B(7,1), C(7,6), D(5,6) What is the perimeter of rectangle ABCD?

Answers

[tex]\begin{gathered} \text{The distance betw}ee\text{n the AB is } \\ d_1=\sqrt[]{(1-1)^2+(7-5)^2} \\ d_1=2 \\ \text{Now, the distance betw}en\text{ the C and D,} \\ d_2=\sqrt[]{(6-6)^2+(5-7)^2} \\ d_2=2 \\ \text{The perimeter o the rectangle is,} \\ P=2(d_1+d_2) \\ P=2(2+2) \\ P=8\text{ unit} \end{gathered}[/tex]

Write an equation that passes through the given points and is perpendicular to the line , (-3,1); y=-5x+2, write it in slope-intercept form pls.

Answers

The equation of the line that passes through point (-3,1) and perpendicular to y=-5x+2 is y = (1/5)x + 8/5.

What is the equation of line that passes through the given points and is perpendicular to the given line?

Given the data in the question;

Equation of line: y = -5x + 2Point: (-3,1)

First we determine the slope of the initial line using the slope intercept-form. y = mx + b

y = -5x + 2

Compared with the slope intercept form,

Slope m = -5

Now, for the equation of line perpendicular to the initial line, its slope must be a negative reciprocal of the initial slope.

Hence, slope of the perpendicular line is;

Slope m = -1/(-5) = 1/5

To find the equation of the perpendicular line, we use the point slope formula.

y - y₁ = m( x - x₁ )

Plug in the slope m ( 1/5) and point (-3,1).

y - 1 = (1/5)( x - (-3) )

y - 1 = (1/5)( x + 3 )

Convert to slope-intercept form.

y - 1 = (1/5)( x + 3 )

y - 1 = x/5 + 3/5

y = x/5 + 3/5 + 1

y = x/5 + 3/5 + 1

y = x/5 + 8/5

y = (1/5)x + 8/5

Therefore, the equation of the perpendicular line is y = (1/5)x + 8/5.

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A $40 phone case is taxed with
an 8% sales tax. How much tax will be
paid?

Answers

Answer: $3.20 is the sales tax

Step-by-step explanation:

[tex]\frac{8x40}{100} =3.2[/tex] (8 times 40 divided by 100)

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trucks in a delivery fleet travel a mean of 80 miles per day with a standard deviation of 26 miles per day. the mileage per day is distributed normally. find the probability that a truck drives at least 113 miles in a day. round your answer to four decimal places.

Answers

Answer:

0.1037

Step-by-step explanation:

9th grade math helppp

Answers

Answer:

b

Step-by-step explanation:

zimak bought 3 xylobars and 5 5 yackities from the intergalactic candy store for 1.75 jeejunu paid1.88 and got 4 xylobars and 1 yackity how much would dado pay for 1 xylobar and 2 yackities

Answers

For 1 xylobar and 2 yackities Dado would pay $0.61   .

In the question ,

it is given that

Zimak paid $1.75 for 3 xylobars and 5 yackities .

let the price of 1 xylobar = x

and let the price of 1 yackities = y

According to the question

3x+5y=1.75    ...(i)

Jeejunu paid $1.88 for 4 xylobars and 1 yackity .

So , equation becomes

4x+y=1.88    ...(ii)

y = 1.88-4x

substituting it in equation (i), we get

3x + 5(1.88 - 4x) = 1.75

3x + 9.4 - 20x = 1.75

20x-3x = 9.4 - 1.75

17x = 7.65

x = 7.65/17

x = 0.45

So, the price of 1 xylobar = $0.45

put x = 0.45 in y= 1.88-4x , we get

y = 1.88 - 4(0.45)

y = 1.88 - 1.8

y = 0.08

So , the price of 1 yackity is $0.08   .

So, For 1 xylobar and 2 yackities , Dado would pay

= x+2y

= 0.45 + 2(0.08)

= 0.45+0.16

= 0.61

Therefore , for 1 xylobar and 2 yackities Dado would pay $0.61   .

The given question is incomplete , the complete question is

Zimak bought 3 xylobars and 5 yackities from the intergalactic candy store for $1.75 . Jeejunu paid  $1.88 and got 4 xylobars and 1 yackity . How much would dado pay for 1 xylobar and 2 yackities ?

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DOES ANYONE KNOW THE ANSWERSSSS

65 pt

Answers

Answer:

3.75 cups of flour

2.5 cups of sugar

1.25 cups of butter

Step-by-step explanation:

Hello!

Let the amount of sugar used be x:

Flour = 1.5xButter = 0.5x

The total sum of ingredients should be 7.5 cups, so we can add x, 1.5x, and 0.5x and set it to 7.5.

Solve for xx + 0.5x + 1.5x = 7.53x = 7.5x = 2.5

Clifford needs 2.5 cups of sugar.

The amount of flour can be found by multiplying 2.5 by 1.5: 3.75 cups

The amount of butter can be found by multiplying 2.5 by 0.5: 1.25

Clifford needs 3.75 cups of flour, 2.5 cups of sugar, and 1.25 cups of butter.

3 3/4 cups of flour
2 1/2 of sugar
1 1/4 of butter

I need help please. Find the distance between Points U and Q.

Answers

Answer:

1 unit

Step-by-step explanation:

- 1 1/2 - (- 2 1/2)

= 1 unit

The listed price of the pair of pants was $38, but the price with tax came to $39.14. Find the percent sales tax.

Answers

well, the difference is 39.14 - 38 = 1.14, so that's the tax.

if we take 38 to be the 100%, just the listed price alone, what is 1.14 off of it in percentage?

[tex]\begin{array}{ccll} amount&\%\\ \cline{1-2} 38 & 100\\ 1.14& x \end{array} \implies \cfrac{38}{1.14}~~=~~\cfrac{100}{x} \implies 38x=114\implies x=\cfrac{114}{38}\implies x=3[/tex]

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