calculate the fractional saturation for hemoglobin when the partial pressure of oxygen is 44 mm hg . assume hemoglobin is 50 % saturated with oxygen at a partial pressure of 26 mm hg and that the hill coefficient is 3.

Answers

Answer 1

The fractional saturation for hemoglobin is 0.8290 when the partial pressure of oxygen is 44 mm hg.

The fractional saturation for hemoglobin can be described as the ratio of the total hemoglobin which is oxygenated.

The fractional saturation for hemoglobin can be calculated by using the following formula;

FS = (partial pressure of oxygen)^n ÷ (partial pressure of oxygen at which hemoglobin is 50% saturated)^n + (partial pressure of oxygen)^n

Here n represents the hill coefficient

Substituting the values in this formula to determine the fractional saturation;

Fractional saturation = (44)³ / (26)³ + (44)³

Fractional saturation = 85,184 / 17,576 + 85,184

Fractional saturation = 85,184 / 102,760

Fractional saturation = 0.8290

Therefore, the fractional saturation for hemoglobin is calculated to be 0.8290 when the partial pressure of oxygen is 44 mm hg.

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Related Questions

what is the population density if ther are 200 deer in 20 sqiare kilomemter

Answers

The QDMA spatial map depicting deer density (deer per square mile) was digitized across the eastern United States

A cell goes through a predictable pattern of phases known as the Cell Cycle, which results in division of the cell to form two daughter cells. In order for a cell to successfully complete a cycle, what process must occur?

Answers

In order for a cell to successfully complete a cycle, the process must occur as the duplicated chromosomes are aligned, separated, and transferred to the cell's poles opposite during the multi-step process known as the mitotic phase. Following this, the cell division occurs into two brand-new, identical daughter cells.

The M phase is a term used to describe the process of mitosis or cell division. Here, the cell divides to create two new, identical daughter cells using previously replicated DNA and cytoplasm. The four basic phases of mitosis are prophase, metaphase, anaphase, and telophase. A cell must grow, replicate its DNA, and physically separate into two daughter cells before it can divide. These actions are carried out by cells in a cell cycle, an ordered and predictable succession of processes.

The cell cycle is a cycle as opposed to a linear pathway because, at the conclusion of each cycle, the two daughter cells can restart the entire process from scratch. The cell cycle is divided into two main phases eukaryotic cells, or cells containing a nucleus: the interphase and the mitotic (M) phase.

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Can you list 1-6 Energy in the form of?

Answers

1. Energy in the form of Light (Solar energy) is converted into Glucose and Oxygen by photosynthesis.

2. Glucose

3. Oxygen

4. Energy in the form of ATP molecules drives cellular functions.

5. Carbon Dioxide

6. Water

Green plants and certain other species employ a process called photosynthesis to create nutrition from carbon dioxide and water. In most cases, the green pigment chlorophyll is used in photosynthesis in plants, and oxygen is produced as a byproduct.

What is Cellular Respiration?Cellular respiration is the method by which biological fuels are converted into a form that can be oxidized in the presence of an inorganic electron acceptor, such as oxygen, to provide a significant quantity of energy that powers the large-scale synthesis of ATP. Adenosine triphosphate (ATP) is created by cellular respiration, a series of metabolic reactions and events that take place in an organism's cells in order to remove waste products after converting chemical energy from foods into ATP. As a result of the catabolic events that occur during respiration, energy is released when big molecules are broken down into smaller ones. One of the main processes a cell uses to release chemical energy to power cellular activity is respiration. Many biochemical stages, some of which are redox reactions, contribute to the overall reaction.The delayed, controlled release of energy from the succession of reactions makes cellular respiration a peculiar combustion reaction, despite the fact that it is strictly one.

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12. Near the equator, rising air is associated with a pressure zone known as the
O
O
tropical low
tropical high
equatorial low
equatorial high

Answers

Near the equator, rising air is associated with a pressure zone known as the equatorial low.

What is equator?

Equator: A large circle that circles the planet evenly in all directions and that is perpendicular to the axis of the planet. The geographic Equator, also known as the terrestrial Equator, is the imaginary line on the surface of the Earth from which latitude is calculated; it is the line at 0° latitude. It separates the Earth into the Northern and Southern hemispheres.

A pressure region known as the equatorial low is connected to rising air close to the equator. This type of zone experiences rainy weather and weak wind movement. One of the hottest places in the planet is there. A low-pressure area is also produced by it. Equatorial lows and doldrums are some names for it.

Hence Equatorial low is the appropriate answers.

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Is a table abiotic or biotic

Answers

Answer:

Abiotic

Explanation:

It's abiotic because it's not alive as it does not have any cells.

craniostenosis is the premature fusion of one or more skull sutures in an infant. predict what problem may arise if the skull sutures prematurely ossify during infancy.

Answers

The problem which may arise if the skull sutures prematurely ossify during infancy is that the baby's head will stop growing in only that part of the skull.

What is a Suture?

This is referred to as the tissues which are present in the skull and helps connects the bones present in the head together and in some instances they ossify prematurely during infancy which is known as craniostenosis.

When this occurs, the baby's head will stop growing in only that part which may lead to an abnormal shape and also different forms of neurological issues and complications may arise.

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A scientist is studying mold cultures. She places different foods in each dish for the molds. She notices that molds with cereal for food are much lighter in color than molds with vegetables for food, and records it in her journal. This is an example of a ________________.


Qualitative Observation


Quantitative Observation


Inference


Prediction

Answers

the veggies and and the cereal both have completely different texture in other words they have a difference in Qualitative also in other words quality, for example i could say the quality of a rug and the quality of a carpet, also both with texture differences and they’re different if you touch both of them, i have no idea if this is right but yeah qualitative is my guess, if its right then i hope it helps

how do the ions move between the pond water and the plant cells using active transport?​

Answers

Answer:

For plants to take up mineral ions, ions are moved into root hairs, where they are in a higher concentration than in the dilute solutions in the soil. Active transport then occurs across the root so that the plant takes in the ions it needs from the soil around it. Active transport in animals

Explanation:

Which is an advantage of a natural-gas-burning power plant over an oil-burning power plant?

A.It releases more energy.
B.It uses a renewable resource.
C.It releases fewer pollutants.
D.It does not release greenhouse gases

Answers

Answer:  C.) It releases fewer pollutants.

Explanation:  Natural-Gas has less Co2 that is released when it burns, meaning that it’s a better option for a fuel source if you don’t want to have pollutants that coal or oil release.  Although both fuel sources produce similar amounts of energy anyhow.

In what phase of meiosis are sister chromatids separated and pulled to opposite ends of the cell? anaphase i anaphase ii metaphase ii metaphase i

Answers

The correct answer for this question is option b Anaphase ii for the question

The sister chromatids are divided and dragged to the cell's opposing ends during meiosis' Anaphase II. The two chromatids of each chromosome shift to opposing poles on the spindle following the separation of the centromeres (to which spindle fibres are linked) during metaphase II. The dissociated chromatids are now referred to as individual chromosomes.

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The cytoplasm of a cell is a thick solution consisting of water and dissolved salts and proteins.

A cell is placed in a beaker of distilled water, which is pure water with nothing dissolved in it.

a) Explain the relationship between the fluid inside the cell and the fluid in the beaker. Make sure to include the appropriate terms (isotonic, hypertonic, hypotonic) in your answer.

b) What will eventually happen to the cell in the beaker?

Answers

Cytoplasm is the fluid which is present inside the cell. It is separated from the surrounding by the presence of a cell membrane. All the organelles are present in the cytoplasm of cell.

What is Cytoplasm?

Cytoplasm is the fluid which is present inside the cell. It is found in all types of cells. All the cell organelles are found in this cytoplasm. The cytoplasm contains dissolved solutes and organelles in it.

When a cell is placed in a beaker full of distilled water than it is an example of hypotonic solution. A hypotonic solution is one in which the concentration of solutes are more in the cell and less in the surrounding or solution in which the cell is placed. This results in the endosmosis of cell, in this the water enters inside the cell by osmosis through the cell membrane and the cell swells up and increase in size.

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dipalmitoylphosphatidylcholine, also known as dppc, is a component of lung surfactant that aims to reduce surface tension of mucus and liquid within the lungs. in order for this phospholipid to work effectively, it must be modified in vivo. predict the hydrolyzed version of dppc and briefly explain how its monomers are effective in acting as a surfactant. 2. when recovering soap from the final step of the reaction, there can be some discrepancies in your mass recording that deviate from the true value. explain what would cause this difference in theoretical mass of soap vs. recovered mass of soap if

Answers

dipalmitoylphosphat Contains dipalmitoylphosphatidylcholine been added to surfactant? Idylcholine, sometimes referred to as dppc, is a lung surfactant component that works to lower surface tension.

The cohesive state that develops at a liquid-liquid or liquid-gas contact is referred to as surface tension. This happens in the lungs at the point where the alveolar membrane and the airway meet. Alveoli are drawn together as a result of increased cohesion caused by increased surface tension.

How does surface tension affect lung compliance?

Surfactant synthesis lowers surface tension within the alveoli to prevent collapse. Surface tension can be reduced to more readily obtain compliance. Together, the chest wall and lungs make up the combined compliance system.

Dipalmitoylphosphatidylcholine, a phospholipid particularly, makes up the majority of the lipid content and is what gives surfactant its biophysical properties.

Water has a high surface tension due to the strong cohesive interactions between its molecules. Surfactants disrupt these interactions as they absorb. Surface tension will drop because the intermolecular interactions between the water molecule and the surfactant are substantially lower than those between two water molecules.

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how does compartmentalization enable the evolution of larger cells?

Answers

Answer:

Separating the cells into different parts allows for the formation of specific microenvironments within the cell. This compartmentalization helps the organelles and cell components to function within their own boundary. So, eukaryotic cells evolved to become super-efficient spaces where multiple activities take place.

The larger molecules can not cross the membrane without the added help of the purple channel protein. Why is their movement across the membrane considered passive transport?

1. their movement across the membrane is not considered passive transport. passive transport only includes diffusion and not the use of channel proteins.

2. passive transport is used to describe any movement across the membrane. since the larger molecules can cross the membrane, this makes their movement a form of passive transport

3. they are crossing passively because they are not attacking the cell membrane

4. no energy input is involved in their movement across the membrane. passive transport requires no energy to be involved.

Answers

Larger molecules are unable to cross the membrane without the assistance of the purple channel protein. Their movement across the membrane requires no energy input; passive transport requires no energy. Thus option 4 is correct.

What is passive transport?

Passive transport is defined as the movement of ions and molecules along a concentration gradient in the absence of external energy.

It is also defined as a type of membrane transport in which substances are moved across cell membranes without the use of energy.

Active transport is defined as a process in which molecules move from a lower concentration region to a higher concentration region.

It can also be defined as the process of transporting molecules across a cellular membrane using cellular energy.

Thus, larger molecules are unable to cross the membrane without the assistance of the purple channel protein. Their movement across the membrane requires no energy input; passive transport requires no energy. Thus option 4 is correct.

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Question 7(Multiple Choice Worth 2 points)
(02.07 MC)
Which of the following steps is required after biological processes have broken down organic material in wastewater?

A-Water is placed in an aeration basin to increase oxygen.

B-Primary clarifiers separate solids from the wastewater.

C-Filtration removes rocks and pebbles from the water.

D-Disinfection purifies water before it is released.

Answers

The step required after biological processes have broken down organic material in wastewater is: (C) Filtration removes rocks and pebbles from the water.

Biological process of waste water treatment is the method that makes the use of microorganisms to break down the organic waste present in the water. It is also called the conventional method and is the most commonly used one.

Filtration is the second last step of biological process where the suspended solids like tiny rocks and pebbles are removed before the purified water is sent for disinfection. It is an optional step because if there are no suspended particles than the water is subjected to direct disinfection.

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please Explain how living and non-living things could interact in a salt water ecosystem.

Answers

The salinity of the water in the ecosystem must be within range in order to allow the organisms to survive.

What is ecosystem?

Recall that the ecosystem is a unit that is composed of living and non living parts that are interdependent on each other and there is an exchange of materials and energy within the system. The energy is passed across the system via the food chains and the food webs that exists in the ecosystem.

In this case we have a salt water system. Note that the salinity of the ecosystem affects the kind of organisms that can survive in the system. Thus, we know that the salinity is a non living factor but it does affect how the organisms in the salt water thrives.

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You are studying a gene that, when mutant, causes oligodendrocytes to enwrap sections of axon so that nodes of ranvier are more closely spaced. What is the likely effect on nerve impulses?.

Answers

Answer:

They will travel slower.

Explanation:

fermentation generally alters the substrate and produces an acidic or alkaline byproduct. this preserves food because choose one: a. microbes prefer neutral ph to grow. b. oxygen is absent. c. free radicals form and destroy the microbial genome. d. the microbes that might use the food as a substrate generally cannot tolerate non-neutral phs..

Answers

Option C is correct. Fermentation is a process that uses microorganisms to break down large organic molecules into smaller ones.

Yeast enzymes, for example, convert sugars and starches to alcohol, whereas proteins are converted to peptides/amino acids. Fermentation is an ancient food preservation technique that involves the breakdown of carbohydrates such as starch and sugar by bacteria and yeast. Kimchi, sauerkraut, kefir, tempeh, kombucha, and yogurt are all examples of fermented foods. Fermentation is a widely used and ancient method of food preservation. Fermentation not only increases a food's shelf life and microbiological safety, but it can also make some foods more digestible and, in the case of cassava fermentation, reduces the substrate's toxicity.

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Would the atmospheric concentration of oxygen increase or decrease after the bubonic plague?

Answers

Answer:The Great Oxidation of Earth’s atmosphere about 2.3 billion years ago began a series of geochemical events leading to elevated oxygen levels for the next 200 million years, with a collapse to much lower levels as these events played their course. This sequence of events is represented in rocks from the Republic of Gabon. We show oxygenation of the deep oceans when oxygen levels were likely their highest. By 2.08 billion years ago, however, oxygen dropped to levels possibly as low as any time in the last 2.3 billion years. These fluctuations can be explained as a direct consequence of the initial oxygenation of the atmosphere during the Great Oxidation Event.

Explanation:

What u. S. State includes areas that have a subarctic climate that supports a variety of wildlife, including grizzly bears, bald eagles, wolves, and bobcats?.

Answers

Alaska area that have a subarctic climate that supports a variety of wildlife, including grizzly bears, bald eagles, wolves, and bobcats.

Long, chilly (sometimes very chilly) winters and brief, mild to cool summers define the subarctic climate, also known as subpolar climate or the boreal climate. It can be found on enormous land masses, frequently away from the regulating effects of an ocean, typically at latitudes between 50° and 70°N north, poleward of the humid continental climates. The regions with subarctic or boreal climates are where the chilly air that impacts temperate latitudes to the south in winter originates.

The temperature can drop below 50 °C (58 °F) in the winter and can rise above 26 °C (79 °F) in the summer in this type of climate, which has some of the most dramatic seasonal temperature fluctuations on the globe.

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Assuming sexual reproduction and that no mutations have occurred, which of the following offspring genotypes is NOT possible for the given parent genotypes?

Answers

Genotype B is NOT possible for the given parent genotypes.

This genotype resembles one parent's genotype. It is based on the supposition that gamete fusion and chromosomal nondisjunction did not take place. In sexual reproduction, the child receives half of its chromosomes from each parent, hence the offspring cannot have the same genotype as one parent. This explains why, throughout the meiotic process of creating gametes, the number of chromosomes is cut in half.

What is genotype?

An organism's genotype is made up of all of its genetic components. The alleles or variations that an individual carries in a specific gene or genetic region are also referred to as the genotype.

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While viewing a specimen under high power of a compound light microscope, a student noticed that the specimen was out of focus. Which part of the microscope should the student turn to obtain a clearer image under LOW power?

Answers

Answer: fine adjustment

Explanation:

To obtain a clearer image under low power on a compound light microscope, the student should adjust the focus using the coarse focus knob.

The compound light microscope typically has two focusing knobs:

The coarse focus knobThe fine focus knob.

The coarse focus knob is used to make larger adjustments to the focus.

When the student noticed that the specimen was out of focus under high power, they can switch to low power and then use the coarse focus knob to bring the specimen into focus.

By turning the coarse focus knob clockwise or counterclockwise, the student can move the objective lens closer to or farther away from the specimen, which will help them obtain a clear image.

Thus, the learner should use the coarse focus knob on a compound light microscope to change the focus in order to get a crisper image at low power.

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In the citric acid cycle, succinate dehydrogenase catalyzes the conversion of succinate to fumarate. This reaction is inhibited by malonate, which resembles succinate but cannot be acted upon by succinate dehydrogenase. Increasing the ratio of succinate molecules to those of malonate in the reaction reduces the inhibitory effect of malonate. What role does malonate play with respect to succinate dehydrogenase?.

Answers

The role that malonate play with respect to the enzyme succinate dehydrogenase is as an enzyme inhibitor.

What are enzymes?

Enzymes are biological catalysts that act to alter the rate of the biochemical reactions occurring in the body.

Enzymes are very important in metabolic reactions as, without these enzymes, most of all the metabolic reactions occurring on them will never be possible.

Most enzymes are proteins and possess the following properties;

they are specific in their actionthey are denatured by heat and too-high or too-low pHthey speed up reaction rates but remain unchanged at the end of the reactionthey can be inhibited or modified

The citric acid cycle has many enzymes that act on different substrates to form products.

However, if a particular molecule binds to the enzyme, but does not result in the formation of a product, but rather prevents the binding of the enzyme-substrate, that molecule is an enzyme inhibitor.

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A concept that asserts fundamental principles of justice and implies the
administration of laws that do not violate the sacredness of private rights
is called:
O Due Process of Law
O Definite Sentence
O Dual Courts
O Durham Rule

Answers

A concept that asserts fundamental principles of justice and implies the administration of laws that do not violate the sacredness of private rights exists comprehended Due Process of Law.

What is meant by Due Process of Law?

To ensure that all of the person's legal rights are honored, the state must apply all relevant legal laws and principles to the case. This is known as due process of law. Due process safeguards a person's rights and balances the power of the law.

The U.S. Supreme Court gives these provisions a broad interpretation and comes to the conclusion that they offer three types of protection: procedural due process (in civil and criminal proceedings); substantive due process, which forbids the use of vague laws; and they serve as the means of incorporating the Bill of Rights.

The Fifth Amendment is divided into five rights or protections: the right to a jury trial when you are accused of a crime; the right to be innocent unless proven guilty; the right to an impartial jury; the right not to be forced to testify against your will; and the right to a fair trial.

Therefore, the correct answer is option a) Due Process of Law.

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Briana finds pieces of her hair in her brush. Why is she still able to grow more hair?.

Answers

Answer:

Brushing your hair stimulates blood flow to the scalp, which helps bring more nutrients to follicles to promote hair growth.

Explanation:

which type of fiber could be considered the longest? group of answer choices postganglionic parasympathetic preganglionic parasympathetic preganglionic sympathetic postganglionic sympathetic

Answers

Preganglionic parasympathetic is the type of fiber that could be considered the longest.

The gastrointestinal tract is supplied by preganglionic neurons from both the cranial and sacral divisions of the parasympathetic nervous system. With the exception of a few numbers that innervates the mouth and pharynx, the cranial parasympathetic preganglionic nerve fibers move along the vagus nerve.

Preganglionic fibers are all cholinergic (i.e., they employ acetylcholine as a neurotransmitter) and myelinated, whether they are in the sympathetic or parasympathetic divisions.

Because they are situated inside or close to the effector organs, parasympathetic ganglia have lengthy preganglionic fibers and small postganglionic fibers. Given their paravertebral chain location, sympathetic ganglia have lengthy postganglionic fibers and small preganglionic fibers.

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how that food molecules and oxygen transfer energy to the cell to support life’s processes, including controlling body temperature, despite losing energy as heat.

Answers

Cellular respiration is the process in which the food molecule along with oxygen is broken which provides energy to the muscle and tissue.

Why molecule is transported to the cell?

Cellular respiration is a chemical manner in which the bonds of meal molecules and oxygen molecules are broken and new compounds that can deliver strength to muscle tissue are shaped. Cell respiratory releases the electricity had to maintain frame temperature notwithstanding ongoing electricity switch to the surrounding environment.

During cellular respiration, the energy which is present in the food is converted into the king of energy that is used by the body's cells. In this process, glucose and oxygen are converted into carbon dioxide and water, and the whole energy is transferred to ATP. Chemical respiration is the process in which the organism combines oxygen and produces energy which is required for the body's cells.

So we can conclude that cellular respiration is the process in which the food molecule along with oxygen is broken which provides energy to the muscle and tissue.

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What type of organic molecules do these represent

Answers

The organic molecules that are shown in the image are called biological macromolecules.

What are biological macromolecules?

Let us note that a macromolecule is a molecule that is composed of smaller units. These smaller units are called monomers. It then follows that we can form the macromolecule by the agglomeration of many units of the smaller molecules that we call the monomers.

Biological molecules are the kind of molecules that play various roles in the body. It also implies that almost all of the biological molecules are found almost to exist exclusively in the bodies of the different species of living organisms.

The role that the molecules pay range from the fact that are important in the supply for energy in the cells of living things to the fact that they could be used as the building blocks of the nuclei acids. The biomolecules that are sugars steroids and fats.

The molecules In the question all all organic molecules and are found to be useful in the body hence they are all generally referred to  by the generic name of biological macromolecules.

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which of the statements below correctly describe the structure of a double-stranded dna molecule? multiple select question. the two strands of dna are held together by phosphodiester bonds between bases on opposite strands it contains one strand of dna the bases in the dna molecule point outwards, away from the central axis of the molecule bases on opposite strands are hydrogen bonded together dna strands form a helical structure

Answers

Option B and D are correct. between bases on opposite strands it contains one strand of DNA the bases in the DNA molecule point outwards, together DNA strands form a helical structure.

A DNA molecule is composed of two linked strands that wind around each other to form a twisted ladder in the shape of a helix. Each strand has an alternating backbone of sugar (deoxyribose) and phosphate groups. Each sugar has one of four bases attached to it: adenine (A), cytosine (C), guanine (G), or thymine (T) (T). A) double antiparallel helical strands are the best way to describe the secondary structure of DNA. DNA has a double helix structure, which is made up of two parallel strands that are joined in the middle and twist around each other. It most accurately describes the structure of a DNA molecule. Furthermore, DNA is not a single strand and does not contain amino acids.

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I will give 15 pts and brainly
Which cell organelles is responsible for creating energy? A mitochondria B Golgi apparatus C nucleus D chloroplasts

Answers

Answer:

A mitochondria

Explanation:

They generate most of the chemical energy needed to power the cell's biochemical reactions.

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Write a paragraph proof of your conclusion in part A. To begin your proof, draw radii OA and OC. help please!!!!!!!!!!!! justin has been diagnosed with dissociative identity disorder. one of his personalities was phoebe, who was 6 years old. as justin aged, phoebe did not. phoebe is known as a . If Volume = 216 cm^3, what is the length of one edge of Julie's jewelry box? Find the 11th term of the sequence: 32805, 10935, 3645... executives acquire information about external opportunities and strengths from a variety of reports, including budgets, financial ratios, profit and loss statements, and surveys of employee attitudes and satisfaction. Simplify completely: cos/1sin what unit would you use to measure the length of a parking lot assume time, cost and quality are the three most common factors involved in trade-offs. define what is meant by each and how the impact of each may impact the other two factors? what determines which factor is most important to project success? In what what were the great civilizations of Mxico Central America and Southtowns Amrica have different Pls help Im close finishing this assignment A. No, Alexandra made a mistake going from the given expression to Step 1. Alexandra should have added 18 and 3 before evaluating the exponent. The order of operations says to perform operations inside parentheses before you evaluate exponents.B. No, Alexandra made a mistake going from Step 1 to Step 2. Alexandra should have divided 9 by 9 before adding. The order of operations says to divide before you add.C. Yes, Alexandra's work is correct. Use the vertex (0,3) and a point on the graph (2,7) to find the general form of the equation of the quadratic function. Can someone help me with this? Im not understanding what its asking of me 1. What is the difference between a homogenous and a heterogeneous mixture? 2. Give 3 examples of each mixture and explain its uses in our daily lives. A net force of 20 Newtons acts on and object of mass 5.0 kilograms for 5.0 seconds. What is the magnitude of the impulse? Orpheus and Eurydice answer key question 1-5 an astrobiologist independently samples 100 space aliens from a population of size 1000. 20% of the space aliens in the population have three or more sets of pharyngeal jaws. what is the expected number of space aliens to be sampled with three or more sets of pharyngeal jaws? What is x in the table below.Green235610Red691518XAnswer3.333303.333 "Falling off the wagon" is a term to describe Which of the following best describes why Old Man Warner's defense of the lottery is ironic?Question 10 options:A) Old Man Warner never participates in the lottery himself, so he is never at risk.B) Participating in the tradition of the lottery is a terribly uncivilized act.C) The lottery is a tradition that shows that the villagers are civilized.