A prospective groom, who is healthy, has a sister with cystic fibrosis (CF), an autosomal recessive disease. Their parents are normal. The brother plans to marry a woman who has no history of CF in her family. What is the probability that they will produce a CF child? They are both Caucasian, and the overall frequency of CF in the Caucasian population is 1/2500—that is, 1 affected child per 2500. (Assume the population meets the Hardy-Weinberg assumptions.)

Answers

Answer 1

Answer:

Explanation:

From the given information:

Since the parent are normal; Let assume that their trait is Pp

The affected sister  will be recessive in nature, so the trait will be pp

Now, the husband who is the groom will be a carrier with a probability of 2/3 since her sister is affected.

Also, the wife will be carrying a heterozygous trait since she is normal as well.

However, using Hardy-Weinberg assumption:

[tex]q^2 = \dfrac{1}{2500}= 0.0004[/tex]

[tex]q = \sqrt{0.0004}[/tex]

q = 0.02

Recall that:

[tex]p+q =1 \\ p = 1 - q \\p = 1 - 0.02 \\p = 0.98\\[/tex]

Thus, [tex]p^2 = (0.98)^2[/tex]

[tex]p^2 = 0.9604[/tex]

[tex]2pq = 2 \times 0.98 \times 0.022[/tex]

2pq = 0.0392

Finally, the required probability that there will be an affected offspring amongst the family is:

[tex]= \dfrac{1}{4} \times \dfrac{2}{3} \times 0.0392[/tex]

[tex]= \dfrac{1}{153}[/tex]


Related Questions

A scientist helps a colleague do a better experiment by:
O A. refusing to consider an alternative interpretation of results.
B. suggesting that unrepeatable results are still reliable.
C. making up observations that are hard to obtain directly
D. sharing the cost of an expensive tool or instrument.

Answers

Answer:

I think C

Explanation:

it is good reason

The scientist that helped to colleague for doing a good experiment when the expensive tool or instrument should be shared.  

What is an experiment?

An experiment refer to the procedure where it should be carried out for supporting or refuting a hypothesis. It provides the cause and effect relationship by represent the result that arise at the time when the specific factor should be changed.

And,  when the expensive tool cost should be shared so the more good experiment should be conducted.

hence, the option d is correct and the rest options should be incorrect.

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A solid is that form of matter that possesses the following
characteristics___.
a Particles vibrate around fixed axes
b Definite shape
C Definite volume
d All of the above

Answers

all of the above lol.

what is a scienctific theory

Answers

Answer:

" A scientific theory is a well-substantiated explanation of some aspect of the natural world, based on a body of facts that have been repeatedly confirmed through observation and experiment. Such fact-supported theories are not "guesses" but reliable accounts of the real world."

Explanation:

- Eijiro <3

A 1.0-kb DNA fragment from the 5' end of the mouse gene is examined by DNA footprint protection analysis. Two samples are end-labeled with 32P, and one of the two is mixed with TFIIB, TFIID, and RNA polymerase II. Both samples are exposed to DNase I. The results are displayed below. The DNA exposed to proteins is run in the right-hand lane of the gel. Control DNA is in the left-hand lane.

Required:
What length of DNA is bound by the transcriptional proteins?

Answers

Answer:

Explanation:

Proteins, such as RNA (ribonucleic acid) polymerase, were loaded into lane 2. TFIIB and TFIID are two forms of TFII. These proteins attach to the fragment of DNA. Furthermore, these proteins shield DNA from the DNase enzyme, which may trigger DNA to split. As a result of the above findings, we may conclude that the inserting proteins(RNA polymerase, TFIID and TR 8 proteins) cover the area between 500 and 800 bp (base pair) in the DNase I footprinting experiment.

As a consequence, the length duration is 300bp since the promoter area is about 500-800bp and is not digested by DNase after incubation of inserting proteins.

Which of the following is a true statement? Physical property change is always better than chemical property change.
o Physical and chemical propery change can happen at the same time.
Chemical property change is better than physical property change.​

Answers

Answer:

the second one

Explanation:

Sometimes it can be tricky to know whether or not a chemical reaction has occurred. For example, when you melt ice into water, you can write the process in terms of a chemical reaction. However, the chemical formula on both sides of the reaction is the same. Since the chemical identity of the matter in question is unchanged, this process represents a physical change.

Thus melting point is a physical property. On the other hand, flammability is a chemical property of matter because the only way to know how readily a substance ignites is to burn it. In the chemical reaction for combustion, the reactants and products are different.

none are better, depending on for what

What patterns do you see for atmospheric carbon dioxide?
Explain your answer.''

Answers

Answer:

So.... Because of its molecular structure, carbon dioxide is a greenhouse gas, which means it allows visible light from the Sun to pass through the atmosphere while absorbing and reemitting infrared energy, heating the Earth.

Explanation:

The above me is right I was gonna say the same thing!!!

How does stimulus become a memory? stay safe god bless.

Answers

Memories will occur when specific groups of neurons have been reactivated. The stimulus results in any brain in a particular pattern of neuronal activity. Some neurons start to become active in either more or less a particular sequence. Retrieval Cue; a stimulus for remembering information.

How many amperes of current will flow in a circuit if the voltage difference is 9V and the resistance in the circuit is 3Ω

Answers

For your answer it will be 3

dsadasd das sad afsasdasdsa?

Answers

I am sorry what?????

what language is this?

1. What happens in any chemical change?
2. List three signs that a chemical change has occurred.
3. Give an example of a chemical change. Explain why you think it is a chemical change.
4. Why can chemical changes often not be reversed?

Answers

1. Chemical change changes the objects color, shape, form or smell
2.burning something, cooking something and rotting
3. Rusting, I think rusting is a chemical change because the air is rusting a object and the air begins to change the color and shape
4. Because once a chemical change happens it will most of the time happen fast

Hydrogen bonds are formed as a result of which of the following? A. Ionic bonds b. Nonpolar covalent bonds c. Polar covalent bonds d. None of these are correct

Answers

Answer:

C

Explanation:

I believe they're opposite.

Why would a rough, steep mountain habitat have a higher rate of speciation
than a large, open grasslands habitat?
A. The mountain has less variety in the environment.
B. The mountain would cause less fragmentation.
C. The mountain has wider range of environments.
D. The mountain has more resources.

Answers

Answer:

C. The mountain has wider range of environments.

Explanation:

Steep mountain habitat have a higher rate of speciation than a large, open grasslands habitat The mountain has wider range of environments.

What is Grassland habitat?

There are various locations and climates on earth where grassland environments can be found. Depending on where in the world they are and the type of climate there, they may also be referred to as prairies, savannahs, steppes, or pampas.

Because there are few places for animals to hide from predators in grasslands, they have developed underground burrows or grown tall enough to look over thick grasses and shrubs.

Many grasslands have been used for farming because they are suitable for raising crops and providing food for cattle. Yet, this means that grassland animals can no longer reside there.

Therefore,  Steep mountain habitat have a higher rate of speciation than a large, open grasslands habitat The mountain has wider range of environments.

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Water flow improves in the aftermath of a forest fire because
rain always puts out fires.
no living organisms survive fires, decreasing demand.
they clear the land, allowing more water to flow over it.
much of the water in a local watershed will be used to fight the fire.

Answers

A major impact of combustion on water quality is the potential for increased precipitation. Runoff can carry suspended soil particles, dissolved inorganic nutrients, and other materials into nearby rivers and lakes, degrading water quality and damaging fish habitat.

Park Williams, an associate professor of geography at UCLA and lead author of the study, said wildfires burn vegetation that would otherwise draw water from the ground and block precipitation before it reaches the ground. said to improve the flow.

Wildfires increase the vulnerability of watersheds to flooding and erosion, causing short-term and long-term damage to water supplies. may have an impact. The increased cost of treatment, the need for alternative medicine, and reduced storage capacity. Fire as a destructive force can rapidly consume large amounts of biomass and cause adverse effects such as soil erosion, post-fire water runoff, and air pollution.

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Answer: The correct answer is they clear the land, allowing more water to flow over it.

Explanation:  Confirmed correct.

Forest fires clear the underbrush and branches from the forest floor, improving the water flow and saturation.

Circle the trisomy shown on
this karyotope.

Answers

Answer: 13 is a trisomy

Explanation:

B. What is the mass number and charge of the emitted positron?
Mass number:
Charge:

Answers

Answer: A positron or antielectron is the antimatter counterpart to an electron. A positron has the equal or same mass as an electron and a spin of 1/2, but it has an electrical charge of +1.

Explanation:

Anorexics are often hungry but refuse to eat, which is misleading because the literal meaning of anorexia is “__________.” A. unhealthy dieting B. excessive hunger C. excessive weight loss D. loss of appetite

Answers

Answer: D

Explanation:

Answer:

D edge 2021

Explanation:

What adaptation helps the pine tree reduce water loss?
leaves
thorns
Seeds in cones
Woody stems

Answers

Answer:hojas

Explanation:

Answer:

A

Explanation:

Pine trees thankfully have needles, which are thin, waxy leaves that enable them to make food year-round. The waxiness of the needles helps evergreens not lose water to evaporation.

Help me please!!!!!!!!!!!!!!!!!

Answers

Explanation:

B one is the correct answer

Answer:

I think it's X

Explanation:

This model of the cell cycle includes two arrows that each represent a process in the cycle. What do the two arrows represent?

A.Arrow 1 represents interphase, and Arrow 2 represents mitosis.

B.Arrow 1 represents meiosis, and Arrow 2 represents prophase.

C.Arrow 1 represents prophase, and Arrow 2 represents interphase.

D.Arrow 1 represents mitosis, and Arrow 2 represents meiosis. ​

Answers

About the question:

You will find the model of the cell cycle in the attached files

Answer:

A. Arrow 1 represents interphase, and Arrow 2 represents mitosis.

Explanation:

When we talk about the cell cycle, we refer to the interphase and the cell division (mitosis or meiosis).

Interphase: Represented by arrow 1.

The interphase is the previous step before mitosis occurs. The interphase is conformed of the G1, S, and G2 stages.

During the G1 stage, it occurs a high intense biochemical activity. The cell duplicates its size, and the organelles and other molecules and cytoplasmatic structures also double. Some structures, such as microtubules and actin filaments, are synthesized from zero. The endoplasmic reticulum increases in size and produces a membrane for the Golgi complex and vacuoles, lysosomes, and vesicles. During this stage, the pair of centrioles separate, and each centriole duplicates. Mitochondria and chloroplasts also replicate.

During the S stage, the DNI replication process occurs. This is the only stage in which the DNI molecule replicates. The synthesis of histones and other associated proteins also occurs.

G2 stage is the interphase last step. DNI molecule begins to slowly condensate. The centrioles duplication process completes. The spindle fibers get assembled.

Once the whole interphase is completed, mitosis occurs.

Mitosis: Represented in the cycle by arrow 2.

Mitosis is a process by which, from a diploid somatic cell (2n), two daughter diploid cells (2n) are produced. During mitosis, the whole-cell first duplicates and then separates. Mitosis is divided into four phases (these phases are shown in the cycle with different gray color tones). During prophase, chromosomes condensate, and the nuclear membrane breaks. During the metaphase, fibers of the spindle apparatus take chromosomes toward the equatorial cell plane, where they line up. Sister chromatids are holden together until they reach the Anaphase, during which specialized enzymes break the bonds between chromatids and separate them. Each chromatid migrates to one of the poles. In telophase, the new chromosomes are already in the corresponding poles, and the nuclear membrane forms again in each pole. Finally, cytokinesis occurs.

Is a forest area that has been washed away by a flood a primary or secondary area of succession?

Answers

Answer:

I'm pretty sure it's secondary

Explanation:

Secondary succession is a major disturbance such as a fire or a flood

Every cell in your body was produced through successive rounds of mitosis, starting from the zygote.

a. True
b. False

Answers

Answer:

I think that the correct answer is True

A kitten embryo is growing inside the uterus of a cat. What is happening to the cells of the kitten embryo?
A) Mitosis, the cells are differentiating

B) Meiosis, the cells are differentiating

C) Meiosis, the genes are being shuffled around

D) Mitosis, genes are being shuffled around

Please answer and don't put fake answer I really need this right.

Answers

Answer:

A

Explanation:

the cells will start to split causing growth in the embryo

The rotation of the earth causes winds to shift and ocean currents to change. This is an example of?
A) inertia.
B) cyclones.
C) acceleration.
D) topographical variation

Answers

Answer:

d) topographical variation

Explanation:

Protein phosphatase 1 (PP1) catalyzes a reaction which yields products that regulate cell division; consequently, PP1 is a possible drug target to treat certain types of cancers. The PP1 enzyme cata- lyzes the hydrolysis of a phosphate group from myelin basic protein (MBP). The reaction is shown below:
PP1 MBP-phosphate-→ MBP+P,
The activity of PP1 was measured in the presence and absence of the inhibitor phosphatidic acid (PA). The concentration of PA was 300 nM. vo without PA vo with PA released . (mg/mL) mL"1 . min1) mL-1 . min-1) 0.00381 0.00620 0.00931 0.0140 0.010 0.0209 0.0335 0.0419 0.0838 0.015 0.025 0.050
(a) Use the data provided to construct a Lineweaver-Burk plot for the PP1 enzyme in the presence and absence of PA. What kind of inhibitor is PA?
(b) Report the KM and Vmax values for PP1 in the presence and absence of the inhibitor.

Answers

Answer:

Explanation:8iikk

what is type of cell division by which sperms are produced​

Answers

Answer:

Meiosis man

Explanation:

Just meiosis

Answer:

Meiosis is the type of cell division that creates egg and sperm cells.

Explanation:

Extensive damage to oligodendrocytes in the CNS could result in reduced speed of nerve impulses. a breakdown of the blood-brain barrier. loss of the structural framework of the brain. inability to produce scar tissue at the site of an injury. decreased production of cerebrospinal fluid.

Answers

Answer:

Loss of the structural framework of the brain.

Explanation:

Damage to oligodendrocytes in the central nervous system leads to the loss of the structural framework of the brain. oligodendrocytes produce the insulating sheath of axons and we know that axons are the nerve fiber that conducts electrical impulses away from the neuron's cell body. Axons are the primary transmission lines of the nervous system that carries impulse throughout the body so if the oligodendrocytes are damaged then our brain did not work properly.

If oligodendrocytes are damaged, the myelin sheaths around axons can be destroyed. This can lead to a loss of the structural framework of the brain, as the axons will no longer be properly insulated. Hence option C is correct.

Oligodendrocytes are glial cells in the central nervous system (CNS) that are responsible for myelinating axons. Myelin is a fatty sheath that surrounds axons and helps to speed up the conduction of nerve impulses.

The loss of the structural framework of the brain can cause a variety of neurological problems, including:

Reduced speed of nerve impulses. As mentioned above, myelin sheaths help to speed up the conduction of nerve impulses. Without myelin sheaths, nerve impulses will travel more slowly, which can cause problems with coordination, movement, and sensation.

Increased risk of seizures. Seizures are caused by abnormal electrical activity in the brain. When the myelin sheaths around axons are damaged, it can increase the risk of seizures.

Cognitive impairment refers to a decline in thinking and memory skills. Damage to oligodendrocytes can lead to cognitive impairment, as the axons will no longer be able to function properly.

Therefore, option C) loss of the structural framework of the brain is correct.

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A solid is that form of matter that possesses the following
characteristics
a
Particles vibrate around fixed axes
b Definite shape
C Definite volume
d All of the above

Answers

D. All of the above

Explain why atmospheric concentrations of carbon dioxide are expected to increase in the future.

Answers

Answer:

because of factories and cars and smoking

Explanation:

Question: 1-7
Which of the following is NOT a function of the stem in a plant?
o absorb water
store nutrients
produce new plant cells
O support flowers and leaves

Answers

Answer: Absorb water

Explanation: i took the quiz the other guy is wrong

Absorbing the water from soil is function of root and not a stem. Thus, option B is correct.

What is stem?

The structural part of plant, that supports leaves, flowers, and fruits is called as stem. Stems are frequently differentiated for storage, asexual reproduction, protection, or photosynthesis.

The stem is divided into nodes and internodes. Node consist of buds and leaves, that can grow into the branches. It also gives rise to adventitious roots. The function of internode is to distance one node from another.

Stem supports and uprights leaves, flowers and fruits. The stem keeps the leaves in the light and provides the plant with a place to hold the flowers and fruit. It transports fluid between xylem and phloem roots and shoots. Therefore, transportation of water and nutrients is the function of stem, and not absorption. Hence, option B is correct.

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Which are consumers?
SELECT ALL THAT APPLY
a Producers
b Grazers
С
Predators
d Scavengers
e Photosynthesizing plants
f Decomposers

Answers

Answer:

b,c,d,f

Explanation:

they are the ones who consume the produce

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What is the amount of excess reserves if any? of the defense mechanisms proposed by freud, which is exemplified by homophobia? essay about future city Gregs backyard is 47 feet wide. How many yards and feet is this? Using productivity software ensures that the end product will look professional. Shane's auto-parts orders 20 tires from tough tires inc. The truck delivering the tires to Shanes is in an accident and 10 of the tires are damaged. Shane's auto-parts A) cannot reject the entire shipmentB) must still pay for all 20 tires at their original contract priceC) May inspect the tires and accept the shipment with the a deduction in price.D) must reject entire shipment True or False (50 question)_____ 1. The sum of the probabilities can give one and sometimes exceed one_____ 2. The alpha value indicates the % of error allowed in the investigation_____ 3. The critical value is obtained from the formulas applied to each Test_____ 4. 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In the Binomial Distribution the Pr (0) is part of the probabilities.____ 19. In Poison Distribution, N is known and its average N is used.____ 20. Incompatible events are mutually exclusive.____ 21. The [Pr (Oc) + Pr (Not Oc)] can give greater than one, sometimes.____ 22. Incompatible events can be seen in classical probability______23. The variable "eye color" is a qualitative variable, nominal______24. The "scatter diagram" illustrates the relationship between 2 variables.______25. In the range of grouped data you subtract the extreme values.______26. The independent variable is manipulated by the researcher.______27. In Poison, with lambda = 20, then Pr (X >1) = 1 [Pr (0, 1)]______28. In the Binomial distribution, with n=10, the Pr (r > 1) = 1 [Pr (0, 1)]______29. The Pr (Oc) + Pr (Not Oc) = 1______30. In Normal distribution the sum of the Probabilities equals one._______31. In the Binomial Distribution r can be greater than n._______32. 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